Gap junctions support the sustained phase of hypoxic pulmonary vasoconstriction by facilitating calcium sensitization

AIMS: To determine the role of gap junctions (GJs) in hypoxic pulmonary vasoconstriction (HPV). METHODS AND RESULTS: Studies were performed in rat isolated intrapulmonary arteries (IPAs) mounted on a myograph and in anaesthetized rats. Hypoxia induced a biphasic HPV response in IPAs preconstricted w...

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Detalhes bibliográficos
Main Authors: Kizub, Igor V., Strielkov, Ievgen V., Shaifta, Yasin, Becker, Silke, Prieto-Lloret, Jesus, Snetkov, Vladimir A., Soloviev, Anatoly I., Aaronson, Philip I., Ward, Jeremy P.T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718323/
https://ncbi.nlm.nih.gov/pubmed/23708740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvt129
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