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Hypoxic pulmonary vasoconstriction in isolated rat pulmonary arteries is not inhibited by antagonists of H(2)S-synthesizing pathways

An increase in the H(2)S (hydrogen sulphide, hereafter sulphide) concentration in pulmonary artery smooth muscle cells (PASMCs) has been proposed to mediate hypoxic pulmonary vasoconstriction (HPV). We evaluated this hypothesis in isolated rat intrapulmonary arteries (IPAs) by examining the effects...

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Опубликовано в: :J Physiol
Главные авторы: Prieto-Lloret, Jesus, Shaifta, Yasin, Ward, Jeremy P T, Aaronson, Philip I
Формат: Artigo
Язык:Inglês
Опубликовано: BlackWell Publishing Ltd 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303384/
https://ncbi.nlm.nih.gov/pubmed/25630260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.277046
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