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Evaluation of immunogenicity and protective efficacy of orally delivered Shigella type III secretion system proteins IpaB and IpaD

Shigella spp. are food- and water-borne pathogens that cause shigellosis, a severe diarrheal and dysenteric disease that is associated with a high morbidity and mortality in resource-poor countries. No licensed vaccine is available to prevent shigellosis. We have recently demonstrated that Shigella...

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Detalhes bibliográficos
Main Authors: Heine, Shannon J., Diaz-McNair, Jovita, Martinez-Becerra, Francisco J., Choudhari, Shyamal P., Clements, John D., Picking, Wendy L., Pasetti, Marcela F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718310/
https://ncbi.nlm.nih.gov/pubmed/23644075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.04.045
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