Two independent pathways of regulated necrosis mediate ischemia–reperfusion injury

Regulated necrosis (RN) may result from cyclophilin (Cyp)D-mediated mitochondrial permeability transition (MPT) and receptor-interacting protein kinase (RIPK)1-mediated necroptosis, but it is currently unclear whether there is one common pathway in which CypD and RIPK1 act in or whether separate RN...

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Bibliografiske detaljer
Main Authors: Linkermann, Andreas, Bräsen, Jan Hinrich, Darding, Maurice, Jin, Mi Kyung, Sanz, Ana B., Heller, Jan-Ole, De Zen, Federica, Weinlich, Ricardo, Ortiz, Alberto, Walczak, Henning, Weinberg, Joel M., Green, Douglas R., Kunzendorf, Ulrich, Krautwald, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718149/
https://ncbi.nlm.nih.gov/pubmed/23818611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305538110
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