Effect of Hypercholesterolemia on Myocardial Necrosis and Apoptosis in the Setting of Ischemia-Reperfusion

BACKGROUND: Hypercholesterolemia is prevalent in patients who experience myocardial ischemia-reperfusion injury (IR). We investigate the impact of dietary induced hypercholesterolemia on the myocardium in the setting of acute IR. METHODS AND RESULTS: In normocholesterolemic (NC,n=7) and hypercholest...

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Autori principali: Osipov, Robert M., Bianchi, Cesario, Feng, Jun, Clements, Richard T., Liu, Yuhong, Robich, Michael P., Glazer, Hilary P., Sodha, Neel R., Sellke, Frank W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752874/
https://ncbi.nlm.nih.gov/pubmed/19752371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.842724
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