Effect of thrombin fragment (TP508) on myocardial ischemia-reperfusion injury in hypercholesterolemic pigs

Myocardial ischemia-reperfusion (IR) injury occurs frequently in the setting of hypercholesterolemia. We investigated the potential efficacy of a novel thrombin fragment (TP508) on IR injury in a hypercholesterolemic porcine model. Twenty-one hypercholesterolemic male Yucatan pigs underwent 60 min o...

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Detalhes bibliográficos
Main Authors: Osipov, Robert M., Robich, Michael P., Feng, Jun, Clements, Richard T., Liu, Yuhong, Glazer, Hilary P., Wagstaff, John, Bianchi, Cesario, Sellke, Frank W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692770/
https://ncbi.nlm.nih.gov/pubmed/19372304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00071.2009
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