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Effect of Dimerized Thrombin Fragment TP508 on Acute Myocardial Ischemia Reperfusion Injury in Hypercholesterolemic Swine

The thrombin-related peptide TP508 is a 23-amino acid monomer that represents a portion of the receptor binding domain in the thrombin molecule. TP508 is also known to readily convert to a dimer in an aqueous environment. In this study the dimeric form of TP508 was investigated in a porcine model of...

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Detalhes bibliográficos
Main Authors: Oyamada, Shizu, Osipov, Robert, Bianchi, Cesario, Robich, Michael P., Feng, Jun, Liu, Yuhong, Burgess, Thomas A., Bell, Timothy M., Sheller, Michael R., Sellke, Frank W.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913770/
https://ncbi.nlm.nih.gov/pubmed/20460385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.166348
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