Atorvastatin Increases Myocardial Indices of Oxidative Stress in a Porcine Model of Hypercholesterolemia and Chronic Ischemia

BACKGROUND/AIM: Atorvastatin has previously been shown to reduce the endogenous angiogenic response to chronic ischemia in a porcine model. One possible mechanism for this effect is reduced bioavailability of nitric oxide, a key mediator of angiogenesis, secondary to increased oxygen free radicals....

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Detalhes bibliográficos
Main Authors: Sodha, Neel R., Boodhwani, Munir, Ramlawi, Basel, Clements, Richard T., Mieno, Shigetoshi, Feng, Jun, Xu, Shu-Hua, Bianchi, Cesario, Sellke, Frank W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629376/
https://ncbi.nlm.nih.gov/pubmed/18598320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1540-8191.2008.00600.x
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