Highly potent, synthetically accessible prostratin analogs induce latent HIV expression in vitro and ex vivo

Highly active antiretroviral therapy (HAART) decreases plasma viremia below the limits of detection in the majority of HIV-infected individuals, thus serving to slow disease progression. However, HAART targets only actively replicating virus and is unable to eliminate latently infected, resting CD4(...

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Bibliographische Detailangaben
Hauptverfasser: Beans, Elizabeth J., Fournogerakis, Dennis, Gauntlett, Carolyn, Heumann, Lars V., Kramer, Rainer, Marsden, Matthew D., Murray, Danielle, Chun, Tae-Wook, Zack, Jerome A., Wender, Paul A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Physical Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718093/
https://ncbi.nlm.nih.gov/pubmed/23812750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302634110
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