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Canonical Notch signaling is dispensable for the maintenance of adult hematopoietic stem cells
Gain-of-function experiments have demonstrated the potential of Notch signals to expand primitive hematopoietic progenitors, but whether Notch physiologically regulates hematopoietic stem cell (HSC) homeostasis in vivo is unclear. To answer this question, we evaluated the effect of global deficienci...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3717373/ https://ncbi.nlm.nih.gov/pubmed/18397755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.02.011 |
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