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CD40 regulates human dendritic cell-derived IL-7 production that, in turn, contributes to CD8(+) T-cell antigen-specific expansion
CD40L (CD154) expressed on activated CD4(+) T cells has been shown to provide CD40(+) dendritic cells (DCs), a critical signal for establishing CD8(+) T-cell immunity. CD40L–CD40 interaction leads to DC maturation with IL-12 production and upregulation of various costimulatory molecules. In this stu...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2008
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3717334/ https://ncbi.nlm.nih.gov/pubmed/19002156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2008.80 |
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