Possible role for calmodulin in insulin release. Studies with trifluoperazine in rat pancreatic islets.

The role of calmodulin in insulin secretion from rat pancreatic islets has been examined by the use of trifluoperazine, an inhibitor of calmodulin-Ca++-directed functions. It was found that 30 microM trifluoperazine caused 50% inhibition, and 100 microM, up to 73% inhibition of 16.7 mM glucose-stimu...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Krausz, Y, Wollheim, C B, Siegel, E, Sharp, G W
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1980
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371690/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6156956/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109893
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