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Possible role for calmodulin in insulin release. Studies with trifluoperazine in rat pancreatic islets.

The role of calmodulin in insulin secretion from rat pancreatic islets has been examined by the use of trifluoperazine, an inhibitor of calmodulin-Ca++-directed functions. It was found that 30 microM trifluoperazine caused 50% inhibition, and 100 microM, up to 73% inhibition of 16.7 mM glucose-stimu...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Krausz, Y, Wollheim, C B, Siegel, E, Sharp, G W
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1980
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371690/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6156956/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109893
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