Possible role for calmodulin in insulin release. Studies with trifluoperazine in rat pancreatic islets.
The role of calmodulin in insulin secretion from rat pancreatic islets has been examined by the use of trifluoperazine, an inhibitor of calmodulin-Ca++-directed functions. It was found that 30 microM trifluoperazine caused 50% inhibition, and 100 microM, up to 73% inhibition of 16.7 mM glucose-stimu...
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| Publicado no: | J Clin Invest |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1980
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371690/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6156956/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109893 |
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