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Possible role for calmodulin in insulin release. Studies with trifluoperazine in rat pancreatic islets.

The role of calmodulin in insulin secretion from rat pancreatic islets has been examined by the use of trifluoperazine, an inhibitor of calmodulin-Ca++-directed functions. It was found that 30 microM trifluoperazine caused 50% inhibition, and 100 microM, up to 73% inhibition of 16.7 mM glucose-stimu...

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Bibliografiske detaljer
Main Authors: Krausz, Y, Wollheim, C B, Siegel, E, Sharp, G W
Format: Artigo
Sprog:Inglês
Udgivet: 1980
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC371690/
https://ncbi.nlm.nih.gov/pubmed/6156956
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