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Plasmin promotes foam cell formation by increasing macrophage catabolism of aggregated low density lipoprotein

OBJECTIVE: The plasmin/plasminogen system is involved in atherosclerosis. However, the mechanisms by which it stimulates disease are not fully defined. A key event in atherogenesis is the deposition of LDL on arterial walls where it is modified, aggregated and retained. Macrophages are recruited to...

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Bibliografiske detaljer
Main Authors: Haka, Abigail S., Grosheva, Inna, Singh, Rajesh K., Maxfield, Frederick R.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716867/
https://ncbi.nlm.nih.gov/pubmed/23702659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.301109
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