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P2X7 receptor-induced death of motor neurons by a peroxynitrite/FAS-dependent pathway
The P2X7 receptor/channel responds to extracellular ATP and is associated with neuronal death and neuroinflammation in spinal cord injury and amyotrophic lateral sclerosis (ALS). Whether activation of P2X7 directly causes motor neuron death is unknown. We found that cultured motor neurons isolated f...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3716845/ https://ncbi.nlm.nih.gov/pubmed/23646980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12286 |
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