Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment

BACKGROUND: Signal Regulatory Protein γ (SIRPγ) is a member of a closely related family of three cell surface receptors implicated in modulating immune/inflammatory responses. SIRPγ is expressed on T lymphocytes where it appears to be involved in the integrin-independent adhesion of lymphocytes to a...

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Hlavní autoři: Nettleship, Joanne E, Ren, Jingshan, Scott, David J, Rahman, Nahid, Hatherley, Deborah, Zhao, Yuguang, Stuart, David I, Barclay, A Neil, Owens, Raymond J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716694/
https://ncbi.nlm.nih.gov/pubmed/23826770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-13-13
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