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Crystal structures of penicillin‐binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms

Penicillin‐binding protein 3 (PBP3) from Pseudomonas aeruginosa is the molecular target of β‐lactam‐based antibiotics. Structures of PBP3 in complexes with azlocillin and cefoperazone, which are in clinical use for the treatment of pseudomonad infections, have been determined to 2.0 Å resolution. To...

詳細記述

保存先:
書誌詳細
出版年:FEBS Lett
主要な著者: Ren, Jingshan, Nettleship, Joanne E., Males, Alexandra, Stuart, David I., Owens, Raymond J.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764023/
https://ncbi.nlm.nih.gov/pubmed/26823174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12054
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