Mechanism-based Inhibition of iPLA(2)β Demonstrates a Highly Reactive Cysteine Residue (C651) That Interacts with the Active Site: Mass Spectrometric Elucidation of the Mechanisms of Underlying Inhibition

Lignende værker

• The structure of iPLA(2)β reveals dimeric active sites and suggests mechanisms of regulation and localization
  af: Malley, Konstantin R., et al.
  Udgivet: (2018)
• Analysis and Functional Prediction of Reactive Cysteine Residues
  af: Marino, Stefano M., et al.
  Udgivet: (2012)
• Inhibition of iPLA(2)β and of stretch-activated channels by doxorubicin alters dystrophic muscle function
  af: Ismail, H M, et al.
  Udgivet: (2013)
• 12-LOX catalyzes the oxidation of 2-arachidonoyl-lysolipids in platelets generating eicosanoid-lysolipids that are attenuated by iPLA(2)γ knockout
  af: Liu, Xinping, et al.
  Udgivet: (2020)
• Apoptosis of Insulin-Secreting Cells Induced by Endoplasmic Reticulum Stress Is Amplified by Overexpression of Group VIA Calcium-Independent Phospholipase A(2) (iPLA(2)β) and Suppressed by Inhibition of iPLA(2)β
  af: Ramanadham, Sasanka, et al.
  Udgivet: (2004)