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The structure of iPLA(2)β reveals dimeric active sites and suggests mechanisms of regulation and localization
Calcium-independent phospholipase A(2)β (iPLA(2)β) regulates important physiological processes including inflammation, calcium homeostasis and apoptosis. It is genetically linked to neurodegenerative disorders including Parkinson’s disease. Despite its known enzymatic activity, the mechanisms underl...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5823874/ https://ncbi.nlm.nih.gov/pubmed/29472584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03193-0 |
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