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RecR-mediated Modulation of RecF Dimer Specificity for Single- and Double-stranded DNA

RecF pathway proteins play an important role in the restart of stalled replication and DNA repair in prokaryotes. Following DNA damage, RecF, RecR, and RecO initiate homologous recombination (HR) by loading of the RecA recombinase on single-stranded (ss) DNA, protected by ssDNA-binding protein. The...

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Autors principals: Makharashvili, Nodar, Mi, Tian, Koroleva, Olga, Korolev, Sergey
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615518/
https://ncbi.nlm.nih.gov/pubmed/19017635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806378200
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