A dual role for mycobacterial RecO in RecA-dependent homologous recombination and RecA-independent single-strand annealing

Mycobacteria have two genetically distinct pathways for the homology-directed repair of DNA double-strand breaks: homologous recombination (HR) and single-strand annealing (SSA). HR is abolished by deletion of RecA and reduced in the absence of the AdnAB helicase/nuclease. By contrast, SSA is RecA-i...

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Detalhes bibliográficos
Main Authors: Gupta, Richa, Ryzhikov, Mikhail, Koroleva, Olga, Unciuleac, Mihaela, Shuman, Stewart, Korolev, Sergey, Glickman, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575820/
https://ncbi.nlm.nih.gov/pubmed/23295671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1298
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