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A Quantitative Proteomics-based Competition Binding Assay to Characterize pITAM-Protein Interactions
Characterization of ligand-protein binding is of crucial importance in drug discovery. Classical competition binding assays measure the binding of a labeled ligand in the presence of various concentrations of unlabeled ligand, and typically use single purified proteins. Here we introduce a high-thro...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3715304/ https://ncbi.nlm.nih.gov/pubmed/23611696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac400359t |
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