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A Quantitative Proteomics-based Competition Binding Assay to Characterize pITAM-Protein Interactions

Characterization of ligand-protein binding is of crucial importance in drug discovery. Classical competition binding assays measure the binding of a labeled ligand in the presence of various concentrations of unlabeled ligand, and typically use single purified proteins. Here we introduce a high-thro...

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Bibliografische gegevens
Hoofdauteurs: Hu, Lianghai, Yang, Li, Lipchik, Andrew M., Geahlen, Robert L., Parker, Laurie L., Tao, W. Andy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715304/
https://ncbi.nlm.nih.gov/pubmed/23611696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac400359t
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