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Using competition assays to quantitatively model cooperative binding by transcription factors and other ligands
BACKGROUND: The affinities of DNA binding proteins for target sites can be used to model the regulation of gene expression. These proteins can bind to DNA cooperatively, strongly impacting their affinity and specificity. However, current methods for measuring cooperativity do not provide the means t...
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| I publikationen: | Biochim Biophys Acta |
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| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5623634/ https://ncbi.nlm.nih.gov/pubmed/28774855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2017.07.024 |
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