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Magnetic Levitation as a Platform for Competitive Protein-Ligand Binding Assays

This paper describes a method based on magnetic levitation (MagLev) that is capable of indirectly measuring the binding of unlabeled ligands to unlabeled protein. We demonstrate this method by measuring the affinity of unlabeled bovine carbonic anhydrase (BCA) for a variety of ligands (most of which...

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Detalhes bibliográficos
Main Authors: Shapiro, Nathan D., Soh, Siowling, Mirica, Katherine A., Whitesides, George M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433162/
https://ncbi.nlm.nih.gov/pubmed/22686324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac301121z
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