SI-RNA INHIBITION OF ASPARTYL-ASPARAGINYL β-HYDROXYLASE EXPRESSION IMPAIRS CELL MOTILITY, NOTCH SIGNALING, AND FETAL GROWTH

INTRODUCTION: Aspartyl-asparaginyl-β-hydroxylase (AAH) regulates cell motility and invasiveness by enhancing Notch signaling. Invasive trophoblastic cells, which mediate placentation, normally express high levels of AAH. Previously, we showed that ethanol-impaired placentation is associated with red...

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Bibliographic Details
Main Authors: Gundogan, Fusun, Bedoya, Armando, Gilligan, Jeffrey, Lau, Emily, Mark, Princess, De Paepe, Monique E., de la Monte, Suzanne M
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715112/
https://ncbi.nlm.nih.gov/pubmed/21862239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prp.2011.06.001
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