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SI-RNA INHIBITION OF ASPARTYL-ASPARAGINYL β-HYDROXYLASE EXPRESSION IMPAIRS CELL MOTILITY, NOTCH SIGNALING, AND FETAL GROWTH
INTRODUCTION: Aspartyl-asparaginyl-β-hydroxylase (AAH) regulates cell motility and invasiveness by enhancing Notch signaling. Invasive trophoblastic cells, which mediate placentation, normally express high levels of AAH. Previously, we showed that ethanol-impaired placentation is associated with red...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3715112/ https://ncbi.nlm.nih.gov/pubmed/21862239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prp.2011.06.001 |
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