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d-Propranolol protects against oxidative stress and progressive cardiac dysfunction in iron overloaded rats

d-Propranolol (d-Pro: 2–8 mg·(kg body mass)(−1)·day(−1)) protected against cardiac dysfunction and oxidative stress during 3–5 weeks of iron overload (2 mg Fe–dextran·(g body mass)(−1)·week(−1)) in Sprague–Dawley rats. At 3 weeks, hearts were perfused in working mode to obtain baseline function; red...

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Detalhes bibliográficos
Main Authors: Kramer, Jay H., Spurney, Christopher F., Iantorno, Micaela, Tziros, Constantine, Chmielinska, Joanna J., Mak, I. Tong, Weglicki, William B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715050/
https://ncbi.nlm.nih.gov/pubmed/22913465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/y2012-091
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