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Deletion of the major peroxiredoxin Tsa1 alters telomere length homeostasis
Reactive oxygen species (ROS) are proposed to play a major role in telomere length alterations during aging. The mechanisms by which ROS disrupt telomeres remain unclear. In Saccharomyces cerevisiae, telomere DNA consists of TG((1-3)) repeats, which are maintained primarily by telomerase. Telomere l...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3714315/ https://ncbi.nlm.nih.gov/pubmed/23590194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12085 |
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