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Deletion of the major peroxiredoxin Tsa1 alters telomere length homeostasis

Reactive oxygen species (ROS) are proposed to play a major role in telomere length alterations during aging. The mechanisms by which ROS disrupt telomeres remain unclear. In Saccharomyces cerevisiae, telomere DNA consists of TG((1-3)) repeats, which are maintained primarily by telomerase. Telomere l...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Lu, Jian, Vallabhaneni, Haritha, Yin, Jinhu, Liu, Yie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714315/
https://ncbi.nlm.nih.gov/pubmed/23590194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12085
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