SLX4 contributes to telomere preservation and regulated processing of telomeric joint molecule intermediates

SLX4 assembles a toolkit of endonucleases SLX1, MUS81 and XPF, which is recruited to telomeres via direct interaction of SLX4 with TRF2. Telomeres present an inherent obstacle for DNA replication and repair due to their high propensity to form branched DNA intermediates. Here we provide novel insigh...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Sarkar, Jaya, Wan, Bingbing, Yin, Jinhu, Vallabhaneni, Haritha, Horvath, Kent, Kulikowicz, Tomasz, Bohr, Vilhelm A., Zhang, Yanbin, Lei, Ming, Liu, Yie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2015
Konular:
Genome Integrity, Repair and Replication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499145/
https://ncbi.nlm.nih.gov/pubmed/25990736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv522
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