SLX4 contributes to telomere preservation and regulated processing of telomeric joint molecule intermediates

SLX4 assembles a toolkit of endonucleases SLX1, MUS81 and XPF, which is recruited to telomeres via direct interaction of SLX4 with TRF2. Telomeres present an inherent obstacle for DNA replication and repair due to their high propensity to form branched DNA intermediates. Here we provide novel insigh...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Sarkar, Jaya, Wan, Bingbing, Yin, Jinhu, Vallabhaneni, Haritha, Horvath, Kent, Kulikowicz, Tomasz, Bohr, Vilhelm A., Zhang, Yanbin, Lei, Ming, Liu, Yie
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
Предметы:
Genome Integrity, Repair and Replication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499145/
https://ncbi.nlm.nih.gov/pubmed/25990736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv522
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