SLX4 contributes to telomere preservation and regulated processing of telomeric joint molecule intermediates

SLX4 assembles a toolkit of endonucleases SLX1, MUS81 and XPF, which is recruited to telomeres via direct interaction of SLX4 with TRF2. Telomeres present an inherent obstacle for DNA replication and repair due to their high propensity to form branched DNA intermediates. Here we provide novel insigh...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Sarkar, Jaya, Wan, Bingbing, Yin, Jinhu, Vallabhaneni, Haritha, Horvath, Kent, Kulikowicz, Tomasz, Bohr, Vilhelm A., Zhang, Yanbin, Lei, Ming, Liu, Yie
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499145/
https://ncbi.nlm.nih.gov/pubmed/25990736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv522
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