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SLX4 contributes to telomere preservation and regulated processing of telomeric joint molecule intermediates
SLX4 assembles a toolkit of endonucleases SLX1, MUS81 and XPF, which is recruited to telomeres via direct interaction of SLX4 with TRF2. Telomeres present an inherent obstacle for DNA replication and repair due to their high propensity to form branched DNA intermediates. Here we provide novel insigh...
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| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4499145/ https://ncbi.nlm.nih.gov/pubmed/25990736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv522 |
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