Human RECQL1 participates in telomere maintenance

A variety of human tumors employ alternative and recombination-mediated lengthening for telomere maintenance (ALT). Human RecQ helicases, such as BLM and WRN, can efficiently unwind alternate/secondary structures during telomere replication and/or recombination. Here, we report a novel role for RECQ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Popuri, Venkateswarlu, Hsu, Joseph, Khadka, Prabhat, Horvath, Kent, Liu, Yie, Croteau, Deborah L., Bohr, Vilhelm A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Genome Integrity, Repair and Replication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027191/
https://ncbi.nlm.nih.gov/pubmed/24623817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku200
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