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RECQL4, the Protein Mutated in Rothmund-Thomson Syndrome, Functions in Telomere Maintenance
Telomeres are structures at the ends of chromosomes and are composed of long tracks of short tandem repeat DNA sequences bound by a unique set of proteins (shelterin). Telomeric DNA is believed to form G-quadruplex and D-loop structures, which presents a challenge to the DNA replication and repair m...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3249070/ https://ncbi.nlm.nih.gov/pubmed/22039056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.295063 |
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