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RECQL4, the Protein Mutated in Rothmund-Thomson Syndrome, Functions in Telomere Maintenance

Telomeres are structures at the ends of chromosomes and are composed of long tracks of short tandem repeat DNA sequences bound by a unique set of proteins (shelterin). Telomeric DNA is believed to form G-quadruplex and D-loop structures, which presents a challenge to the DNA replication and repair m...

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Main Authors: Ghosh, Avik K., Rossi, Marie L., Singh, Dharmendra Kumar, Dunn, Christopher, Ramamoorthy, Mahesh, Croteau, Deborah L., Liu, Yie, Bohr, Vilhelm A.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249070/
https://ncbi.nlm.nih.gov/pubmed/22039056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.295063
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