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Coordinated Regulation of Hepatic Energy Stores by Leptin and Hypothalamic Agouti-Related Protein

Like obesity, prolonged food deprivation induces severe hepatic steatosis; however, the functional significance of this phenomenon is not well understood. In this study, we show that the fall in plasma leptin concentration during fasting is required for the development of hepatic steatosis in mice....

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Detalhes bibliográficos
Main Authors: Warne, James P., Varonin, Jillian M., Nielsen, Sofie S., Olofsson, Louise E., Kaelin, Christopher B., Chua, Streamson, Barsh, Gregory S., Koliwad, Suneil K., Xu, Allison W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713731/
https://ncbi.nlm.nih.gov/pubmed/23864684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0830-13.2013
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