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Agouti-related peptide plays a critical role in leptin's effects on female puberty and reproduction
Deficient leptin signaling causes infertility via reduced activity of GnRH neurons, causing a hypogonadal state in both rodents and humans. Because GnRH neurons do not express leptin receptors, leptin's effect on GnRH neurons must be indirect. Neurons within the hypothalamic arcuate nucleus tha...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3882375/ https://ncbi.nlm.nih.gov/pubmed/24169048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00241.2013 |
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