Agouti-related peptide plays a critical role in leptin's effects on female puberty and reproduction

Deficient leptin signaling causes infertility via reduced activity of GnRH neurons, causing a hypogonadal state in both rodents and humans. Because GnRH neurons do not express leptin receptors, leptin's effect on GnRH neurons must be indirect. Neurons within the hypothalamic arcuate nucleus tha...

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Detaylı Bibliyografya
Asıl Yazarlar: Sheffer-Babila, Sharone, Sun, Yan, Israel, Davelene D., Liu, Shun-Mei, Neal-Perry, Genevieve, Chua, Streamson C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2013
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882375/
https://ncbi.nlm.nih.gov/pubmed/24169048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00241.2013
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