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Neuropeptide Y and Agouti-Related Peptide Mediate Complementary Functions of Hyperphagia and Reduced Energy Expenditure in Leptin Receptor Deficiency

Neuropeptide Y (NPY) and agouti-related peptide (AGRP) can produce hyperphagia, reduce energy expenditure, and promote triglyceride deposition in adipose depots. As these two neuropeptides are coexpressed within the hypothalamic arcuate nucleus and mediate a major portion of the obesity caused by le...

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書誌詳細
主要な著者: Luo, Na, Marcelin, Genevieve, Liu, Shun Mei, Schwartz, Gary, Chua, Streamson
フォーマット: Artigo
言語:Inglês
出版事項: Endocrine Society 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040058/
https://ncbi.nlm.nih.gov/pubmed/21285324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1135
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