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Ablation of Leptin Signaling to Somatotropes: Changes in Metabolic Factors that Cause Obesity
Mice with somatotrope-specific deletion of the Janus kinase binding site in leptin receptors are GH deficient as young adults and become obese by 6 months of age. This study focused on the metabolic status of young (3–4.5 month old) preobese mutant mice. These mutants had normal body weights, lean b...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Endocrine Society
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3512011/ https://ncbi.nlm.nih.gov/pubmed/22865370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1331 |
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