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Genetic control of ATGL-mediated lipolysis modulates adipose triglyceride stores in leptin-deficient mice

Dissecting the genetics of complex traits such as obesity allows the identification of causal genes for disease. Here, we show that the BALB/c mouse strain carries genetic variants that confer resistance to obesity induced by leptin-deficiency or a high-fat diet (HFD). We set out to identify the phy...

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Detalhes bibliográficos
Main Authors: Marcelin, Genevieve, Liu, Shun-Mei, Li, Xiaosong, Schwartz, Gary J., Chua, Streamson
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329395/
https://ncbi.nlm.nih.gov/pubmed/22383686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M022467
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