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Leptin receptor modulation of adiposity and fertility
The leptin receptor was discovered as a leptin binding protein, which is highly expressed in the choroid plexus. Mapping of the gene's chromosomal locations in rodents revealed that mutations in Lepr were the basis for obesity/diabetes mutations in rodents and humans. Genetic manipulations that...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818174/ https://ncbi.nlm.nih.gov/pubmed/19854659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2009.07.004 |
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