The Modified Selenenyl Amide, M-hydroxy Ebselen, Attenuates Diabetic Nephropathy and Diabetes-Associated Atherosclerosis in ApoE/GPx1 Double Knockout Mice

Seleno-organic glutathione peroxidase (GPx) mimetics, including ebselen (Eb), have been tested in in vitro studies for their ability to scavenge reactive oxygen and nitrogen species, including hydrogen peroxide and peroxynitrite. In this study, we investigated the efficacies of two Eb analogues, m-h...

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Hauptverfasser: Tan, Sih Min, Sharma, Arpeeta, Yuen, Derek Y. C., Stefanovic, Nada, Krippner, Guy, Mugesh, Govindasamy, Chai, Zhonglin, de Haan, Judy B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712958/
https://ncbi.nlm.nih.gov/pubmed/23874911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069193
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