The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction

BACKGROUND: Vascular dysfunction is a pivotal event in the development of diabetes-associated vascular disease. Increased inflammation and oxidative stress are major contributors to vascular dysfunction. Nrf2, a master regulator of several anti-oxidant genes and a suppressor of inflammatory NF-κB, h...

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Detalhes bibliográficos
Publicado no:Cardiovasc Diabetol
Main Authors: Sharma, Arpeeta, Rizky, Luddwi, Stefanovic, Nada, Tate, Mitchel, Ritchie, Rebecca H., Ward, Keith W., de Haan, Judy B.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335831/
https://ncbi.nlm.nih.gov/pubmed/28253885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-017-0513-y
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