The Modified Selenenyl Amide, M-hydroxy Ebselen, Attenuates Diabetic Nephropathy and Diabetes-Associated Atherosclerosis in ApoE/GPx1 Double Knockout Mice

Seleno-organic glutathione peroxidase (GPx) mimetics, including ebselen (Eb), have been tested in in vitro studies for their ability to scavenge reactive oxygen and nitrogen species, including hydrogen peroxide and peroxynitrite. In this study, we investigated the efficacies of two Eb analogues, m-h...

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Detalhes bibliográficos
Main Authors: Tan, Sih Min, Sharma, Arpeeta, Yuen, Derek Y. C., Stefanovic, Nada, Krippner, Guy, Mugesh, Govindasamy, Chai, Zhonglin, de Haan, Judy B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712958/
https://ncbi.nlm.nih.gov/pubmed/23874911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069193
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