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Functional Redundancy of CXCR3/CXCL10 Signaling in the Recruitment of Diabetogenic Cytotoxic T Lymphocytes to Pancreatic Islets in a Virally Induced Autoimmune Diabetes Model
Cytotoxic T lymphocytes (CTLs) constitute a major effector population in pancreatic islets from patients suffering from type 1 diabetes (T1D) and thus represent attractive targets for intervention. Some studies have suggested that blocking the interaction between the chemokine CXCL10 and its recepto...
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Päätekijät: | , , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
American Diabetes Association
2013
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3712024/ https://ncbi.nlm.nih.gov/pubmed/23434930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1370 |
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