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Intravital imaging of CTLs killing islet cells in diabetic mice

Type 1 diabetes (T1D) is caused by autoimmune destruction of the insulin-producing β cells in the pancreatic islets, which are essentially mini-organs embedded in exocrine tissue. CTLs are considered to have a predominant role in the autoimmune destruction underlying T1D. Visualization of CTL-mediat...

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Detalhes bibliográficos
Main Authors: Coppieters, Ken, Amirian, Natalie, von Herrath, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248300/
https://ncbi.nlm.nih.gov/pubmed/22133877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59285
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