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CXCL10 promotes liver fibrosis by prevention of NK cell mediated hepatic stellate cell inactivation

Chemokines, such as CXCL10, promote hepatic inflammation in chronic or acute liver injury through recruitment of leukocytes to the liver parenchyma. The CXCL10 receptor CXCR3, which is expressed on a subset of leukocytes, plays an important part in Th1-dependent inflammatory responses. Here, we inve...

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Detalhes bibliográficos
Main Authors: Hintermann, Edith, Bayer, Monika, Pfeilschifter, Josef M., Luster, Andrew D., Christen, Urs
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855675/
https://ncbi.nlm.nih.gov/pubmed/20932719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2010.09.003
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