Functional Redundancy of CXCR3/CXCL10 Signaling in the Recruitment of Diabetogenic Cytotoxic T Lymphocytes to Pancreatic Islets in a Virally Induced Autoimmune Diabetes Model

Cytotoxic T lymphocytes (CTLs) constitute a major effector population in pancreatic islets from patients suffering from type 1 diabetes (T1D) and thus represent attractive targets for intervention. Some studies have suggested that blocking the interaction between the chemokine CXCL10 and its recepto...

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Détails bibliographiques
Auteurs principaux: Coppieters, Ken T., Amirian, Natalie, Pagni, Philippe P., Baca Jones, Carmen, Wiberg, Anna, Lasch, Stanley, Hintermann, Edith, Christen, Urs, von Herrath, Matthias G.
Format: Artigo
Langue:Inglês
Publié: American Diabetes Association 2013
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712024/
https://ncbi.nlm.nih.gov/pubmed/23434930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1370
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