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Fulvestrant regulates epidermal growth factor (EGF) family ligands to activate EGF receptor (EGFR) signaling in breast cancer cells

Estrogen receptor-α (ER) targeted therapies are routinely used to treat breast cancer. However, patient responses are limited by resistance to endocrine therapy. Breast cancer cells resistant to the pure steroidal ER antagonist fulvestrant (fulv) demonstrate increased activation of epidermal growth...

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Autori principali: Zhang, Xihong, Diaz, Michael R., Yee, Douglas
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711713/
https://ncbi.nlm.nih.gov/pubmed/23686416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-013-2541-y
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