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Tyrosine kinase signalling in breast cancer: Insulin-like growth factors and their receptors in breast cancer
The insulin-like growth factor (IGF) system exerts pleiotropic effects on mammalian cells. This review focuses on type I IGF receptor (IGF1R)-mediated signal transduction and its relevance in breast cancer. Upon activation by the IGFs, IGF1R, a transmembrane tyrosine kinase receptor, undergoes autop...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC138771/ https://ncbi.nlm.nih.gov/pubmed/11250706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr50 |
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