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Tyrosine kinase signalling in breast cancer: Insulin-like growth factors and their receptors in breast cancer

The insulin-like growth factor (IGF) system exerts pleiotropic effects on mammalian cells. This review focuses on type I IGF receptor (IGF1R)-mediated signal transduction and its relevance in breast cancer. Upon activation by the IGFs, IGF1R, a transmembrane tyrosine kinase receptor, undergoes autop...

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Bibliografische gegevens
Hoofdauteurs: Zhang, Xihong, Yee, Douglas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2000
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC138771/
https://ncbi.nlm.nih.gov/pubmed/11250706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr50
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